Advances in Giardia duodenalis genomics
10.3969/j.issn.1002-2694.2024.00.140
- VernacularTitle:十二指肠贾第虫基因组学研究进展
- Author:
Yi-Zhuo WEI
1
;
Chun-Xiang ZHOU
;
Jing-Jing SUN
;
Long-Xian ZHANG
;
Jun-Qiang LI
Author Information
1. 河南农业大学动物医学院,郑州 450046
- Keywords:
Giardia duodenalis;
genomics;
structural genomics;
comparative genomics;
functional genomics
- From:
Chinese Journal of Zoonoses
2024;40(10):977-983
- CountryChina
- Language:Chinese
-
Abstract:
Giardia duodenalis is a zoonotic intestinal parasitic protozoan that can severely harm human and animal health,and causes substantial economic losses to humans and animal husbandry annually.Currently,no effective drugs and vaccines a-gainst giardiasis are available.With the development of bioinformatics and sequencing techniques,genomic sequencing of the Giardia genome and comparative genomics analysis have advanced understanding of the molecular characteristics of Giardia.This article reviews the current status of genome sequencing,structural genomics,comparative genomics,and functional ge-nomics for Giardia duodenalis,to provide new ideas for understanding the origins,evolution and pathogenic mechanisms of Giardia,to aid in the diagnosis,design of new veterinary drugs,and development of vaccines for giardiasis.
