Epidemiological and Clinical Characteristics of Imported Malaria in Wuhan,China,2012-2019
10.3969/j.issn.1002-2694.2024.00.078
- VernacularTitle:武汉市2012-2019年输入性疟疾流行病学与临床特征分析
- Author:
Shu-Kun YU
1
;
Shou-Nan ZHANG
;
Li ZHANG
;
Yu-Xin WANG
;
Ya-Xin TAN
;
Sheng WEI
;
Zi-Wei SHI
;
Kai WU
;
Zhi-Yang TAO
Author Information
1. 武汉市东西湖区疾病预防控制中心,武汉 430040
- Keywords:
imported malaria;
Plasmodium falciparum;
severe malaria;
migrant workers;
length of stay;
risk factors
- From:
Chinese Journal of Zoonoses
2024;40(6):583-589
- CountryChina
- Language:Chinese
-
Abstract:
Although indigenous malaria has been eliminated in Wuhan since 2013,imported malaria remains a potential threat as an infectious source of local malaria transmission.The epidemiological and clinical characteristics of imported malaria are particularly important in areas where local malaria has been eliminated.This study was aimed at analyzing the epidemiological and clinical characteristics of imported malaria in Wuhan from 2012 to 2019,to provide a basis for further improving the preven-tion and control of imported malaria.Patients in Wuhan diagnosed with imported malaria from January 1,2012,to December 31,2019,were included in this study.A case-control study was con-ducted to analyze the features of patients with severe malaria.Uni-variate and multivariate logistic regression was used to identify risk factors for prolonged hospital length of stay(LOS).Among 229 imported malaria cases,212(92.6％)were in Chinese citizens,and most cases were in men(96.5％).The gender ratio is 28:1,and the age of cases is mainly concertrated between 18 and 50 years old(89.1％).More than 80％of patients were mi-grant workers,and most cases were infections from African countries(92.6％).Plasmodium falciparum(80.8％)was the dominant species.Fifty-three severe malaria cases were identified during the study period.Compared with uncomplicated cases,severe cases tended to occur in patients with no history of malaria(P=0.008),patients infected with Plasmodium falciparum(P=0.009),and patients who were initially misdiagnosed(P＜0.001).The median LOS was 6 days,and the species of infec-tion(Plasmodium falciparum),the use of antimalarial drugs(group B),antipyretic time(longer than 3 days),and the turn-around time of blood smear microscopy(longer than 3 days)were significantly associated with longer LOS(all P＜0.05).Al-though malaria has been eradicated in Wuhan for many years,imported cases continue to pose a threat.Efforts should be made to strengthen malaria knowledge education for outbound personnel.Additionally,medical institutions must enhance diagnosis and treatment capabilities for malaria,and adhere to standardized treatment processes,and the development of drug resistance and occurrence of severe malaria must be prevented.
