Current status and influencing factors of low anterior resection syndrome in rectal cancer patients with sphincter-preserving surgery
10.3760/cma.j.cn115682-20240320-01471
- VernacularTitle:直肠癌保肛术后患者低位前切除综合征发生现状及其影响因素分析
- Author:
Xueqian MA
1
;
Jiaqi XU
;
Yanan YANG
;
Miao YU
;
Hongbo CHEN
;
Baohua LI
Author Information
1. 北京大学第三医院护理部，北京 100191
- Keywords:
Rectal neoplasms;
Sphincter-preserving surgery;
Low anterior resection syndrome;
Emotions;
Sleep
- From:
Chinese Journal of Modern Nursing
2024;30(34):4646-4653
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the incidence of low anterior resection syndrome (LARS) in patients undergoing sphincter-preserving surgery for rectal cancer and analyze related factors.Methods:This study was a cross-sectional survey. From 2021 to 2023, convenience sampling was used to select 195 patients with rectal cancer who underwent sphincter-preserving surgery at Peking University Third Hospital as participants. The patients were surveyed using the General Information Questionnaire, LARS Scale, Visual Analog Score, and Chinese version of Insomnia Severity Index.Results:A total of 195 questionnaires were distributed, and 156 valid questionnaires were collected, with a valid response rate of 80.00% (156/195). The incidence of LARS in 156 rectal cancer patients with sphincter-preserving surgery was 36.54% (57/156), and the incidence of severe LARS was 15.38% (24/156). Binomial Logistic regression analyses showed that gender ( OR=0.445, P=0.034) and preoperative neoadjuvant chemoradiotherapy ( OR=6.343, P<0.01) were influencing factors for the occurrence of LARS in patients with rectal cancer after sphincter-preserving surgery. Preoperative neoadjuvant chemoradiotherapy ( OR=3.322, P=0.047) and intraoperative prophylactic stoma ( OR=4.855, P=0.035) were influencing factors for severe LARS. LARS score was positively correlated with anxiety score ( r=0.238, P=0.003) and total insomnia score ( r=0.168, P=0.036) in patients with rectal cancer who underwent sphincter-preserving surgery. Conclusions:Preoperative neoadjuvant chemoradiotherapy is an independent risk factor for postoperative LARS and severe LARS in rectal cancer patients undergoing sphincter-preserving surgery. LARS is correlated with patients' anxiety and insomnia.
