Seroepidemiological survey of Lyme disease in Urumqi City,Xinjiang,China
10.3969/j.issn.1002-2694.2024.00.055
- VernacularTitle:新疆乌鲁木齐市莱姆病血清流行病学调查
- Author:
Li YANG
1
,
2
;
Zi-Yi ZHANG
;
Tong-Tong SHAO
;
Xin-Ting LI
;
Rong-Jiong ZHENG
;
Shi-Yi WANG
;
Yuan-Zhi WANG
;
Qin HAO
;
Xiao-Bo LU
Author Information
1. 新疆医科大学第一附属医院感染与肝病中心,乌鲁木齐 830000
2. 新疆医科大学第八附属医院呼吸与危重症医学科,乌鲁木齐 830000
- Keywords:
Lyme disease;
seroepidemiology;
Urumqi City
- From:
Chinese Journal of Zoonoses
2024;40(4):334-339
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of Lyme disease in endogenous populations in Urumqi,Xinjiang was investigated.In total,795 serum samples were collected from residents of three townships in the surrounding area of Urumqi City from 2022 to 2023,which included 383 from Lucaogou Town,145 from Shuixigou Town,and,267 from Tori Township.Serum levels of IgG and IgM antibodies were screened with an enzyme linked immunosorbent assay(ELISA)and confirmed by western blot(WB)analysis.Clinical data of WB-positive indi-viduals were collected and comprehensive analysis was con-ducted for case diagnosis.The chi square test was used for statistical analysis of the results and the P＜0.05 was consid-ered statistically significant.In total,110(13.84％)of 795 samples were positive.The positivity rates was higher in females than males[16.26％(73/449)vs.10.69％(37/346),x2=5.076,P=0.024],while there was no significant difference among age groups(x2=2.569,P=0.766).The positivity rates for serum antibodies in Shuixigou Town,Lucaogou Town,and Tuoli Township were 17.98％(48/267),14.48％(21/145),and 10.70％(41/383),respectively,with a significantly higher rate in Tuoli Township than Lucaogou Town(x2=7.041,P=0.008).Of 110 individuals who were initially positive for IgG and IgM antibodies with the ELISA,82(10.31％)were con-firmed positive by WB analysis.In total,20(2.52％)patients were diagnosed with Lyme disease based on clinical manifesta-tions.Lyme disease is epidemic among the population in Urumqi,as the infection rate is higher than the national average.Hence,continued surveillance is recommended for prevention of Lyme disease.
