Tick-borne pathogens infection of rodents at the border of China and the Democratic People's Republic of Korea
10.3969/j.issn.1002-2694.2024.00.053
- VernacularTitle:中朝边境地区野鼠中蜱媒病原体感染调查
- Author:
Zhuo WANG
1
;
Qiong WU
;
Xiao-Yang HUANG
;
Guan-Peng HUANG
;
You-Xin MA
;
En-Rong MAO
;
Guo-Shuang LENG
;
Hong-Min ZHAO
;
Bing LI
;
Yi-Min WU
Author Information
1. 北部战区疾病预防控制中心生物安全科,沈阳 110034
- Keywords:
rodents;
tick-borne pathogens;
coinfections;
polymerase chain reaction
- From:
Chinese Journal of Zoonoses
2024;40(4):323-327
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the existence of tick-borne pathogens infection of rodents at the border of China and the Demo-cratic People's Republic of Korea(DPRK).PCR was used to detect the spotted fever group rickettsiae(SFGR)ompA gene,Ehrlichia chaffeensis(Ec)and Anaplasma phagocytophilum(Ap)16S rRNA,Candidatus Neoehrlichia mikurensis(CNm)groEL gene,Bartonella(Ba)rpoB gene,and Francisella tularensis(Ft)fopA gene in rodents samples collected from Ji'an of Jilin province and Kuandian of Liaoning Province.The positivity rates of 132 wild rats spleen samples,SFGR,Ec,Ap,CNm,Ba,and Ft were 9.85％,12.88％,5.30％,3.79％,51.52％,and 6.06％,respectively,with statistical differences in in-fection rates(x2=149.236,P=0.000).The infection rate of Ba was the highest in wild rats in this area.There was no signifi-cant difference in the infection rate of SFGR,Ec,Ap,CNm,and Ft among different rats species,but there were significant differences in the infection rate of Ba(x2=13.36,P=0.010).The infection rate of Apodemus agrarius was the highest.A-mong 132 wild rats specimens,the coinfection rate of the two pathogens was 15.9％(21/132),with Ba as the main species(15/132),and two cases of coinfection with three pathogens were detected.The infection of six tick-borne pathogens is common in wild rats at the China/DPRK border.Co-infection of two or three pathogens indicates a risk of multiple tick-borne pathogens and mixed natural foci of multiple tick-borne infec-tious diseases.
