Meta-analysis of risk factors for multi-drug resistant organisms infections after liver transplantation
10.3760/cma.j.cn115682-20231109-01968
- VernacularTitle:肝移植术后多重耐药菌感染危险因素的Meta分析
- Author:
Jin YANG
1
;
Na HUI
;
Jiuping WANG
;
Qiao CHENG
;
Meixia ZHANG
Author Information
1. 空军军医大学第一附属医院感染性疾病科，西安 710032
- Keywords:
Meta-analysis;
Liver transplantation;
Multi-drug resistant organisms;
Influencing factors
- From:
Chinese Journal of Modern Nursing
2024;30(29):3980-3986
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate influencing factors of multi-drug resistant organisms (MDROs) infection in patients undergoing liver transplantation and to provide reference for infection prevention and control.Methods:The relevant literatures on the influencing factors of MDROs infection after liver transplantation included in PubMed, Medline, Embase, Wed of Science, China Biology Medicine disc, Wanfang Database, China National Knowledge Infrastructure and VIP were searched by computer, and the search time was from the establishment of databases to September 1, 2023. The languages were limited to Chinese and English. Two evaluators screened literature and extracted data, and used The Newcastle Ottawa Scale to evaluate the quality of the final included literature. Meta-analysis was performed using RevMan5.4 software.Results:Finally, a total of 17 literatures were included, including five case-control studies and 12 cohort studies. The results of Meta-analysis showed that ClassⅡ toⅣ hepatic encephalopathy, renal insufficiency, colonization of drug-resistant organisms before transplantation, performing tracheal intubation, tracheal intubation time greater than or equal to 48 h, tracheal intubation time greater than or equal to 72 h, length of ICU stay, use of antibiotics before transplantation, postoperative bile leakage, postoperative fungal culture of positivity, reoperation after transplantation and hemodialysis were risk factors for MDROs infection after liver transplantation ( P<0.05) . Conclusions:There are many influencing factors for multi-drug resistant organisms infection in liver transplant patients after surgery. Medical staff should be vigilant and identify relevant risk factors, conduct infection risk assessment and take preventive and control measures based on risk factors to improve the prognosis of liver transplant patients.
