Comparison of therapeutic effects of two methods combined with self-expanding metal stent in treatment of obstructive jaundice
- VernacularTitle:两种方法联合胆道自膨式金属支架置入术治疗梗阻性黄疸的疗效对比
- Author:
Chaozhi WANG
1
;
Kun LIU
;
Shan WANG
Author Information
- Keywords: endoscopic retrograde cholangiopancreatography(ERCP); biliary self-expanding metal stent(SEMS)implantation; obstructive jaundice(OJ); jaundice relief rate; liver function
- From: China Journal of Endoscopy 2024;30(10):62-68
- CountryChina
- Language:Chinese
- Abstract: Objective To compare the efficacy of percutaneous transhepatic cholangial drainage(PTCD)and endoscopic retrograde cholangiopancreatography(ERCP)combined with self-expanding metal stent(SEMS)in treatment of obstructive jaundice(OJ).Methods From January 2022 to July 2023,125 OJ patients were selected and grouped into two groups based on treatment plans.The reference group consisted of 62 cases who underwent PTCD combined with biliary SEMS implantation,while the test group consisted of 63 cases who underwent ERCP combined with biliary SEMS implantation.The remission rate of jaundice,liver function,cellular immune function,and complications were compared.Results There was no statistically significant difference in the relief rate of jaundice between the test group(90.48%,57/63)and the reference group(87.10%,54/62)(P＞0.05).After treatment,six measures of liver function in the test group were lower than those in the reference group,three indexes of cellular immune function in the test group were higher than those in the reference group,the differences were significant(P＜0.05).The total incidence of complications in the test group(9.52%,6/63)showed no statistically significant difference compared to the reference group(12.90%,8/62)(P＞0.05).Conclusion ERCP combined with biliary SEMS implantation is superior to PTCD combined with biliary SEMS implantation in improving liver function and enhancing cellular immune function,and there is no difference in jaundice relief rate and incidence of complications compared to PTCD combined with biliary SEMS implantation.
