Longitudinal study on the trajectory and influencing factors of frailty in patients receiving maintenance hemodialysis
10.3760/cma.j.cn115682-20231225-02797
- VernacularTitle:维持性血液透析患者衰弱变化轨迹及影响因素的纵向研究
- Author:
Chuanjing ZHAO
1
;
Wangzhen WANG
;
Hong LIU
;
Gaoyue WANG
;
Jinying YU
;
Shengfei HUANG
Author Information
1. 湖北民族大学附属民大医院血液净化中心，恩施 445000
- Keywords:
Hemodialysis;
Frailty;
Trajectory;
Longitudinal study;
Influencing factor
- From:
Chinese Journal of Modern Nursing
2024;30(24):3237-3242
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the trajectory of frailty changes in patients receiving maintenance hemodialysis and analyze its influencing factors.Methods:Maintenance hemodialysis patients at the Blood Purification Center of the Minda Hospital of Hubei Minzu University from January to October 2022 were selected by convenience sampling. The Clinical Frailty Scale (CFS) was used to survey patients at the start of dialysis and one, three, six, and 12 months of dialysis. Latent class growth modeling was employed to identify the potential classes of frailty trajectory changes and analyze the influencing factors of these classes.Results:A total of 255 questionnaires were distributed, with 212 valid responses, yielding an effective response rate of 83.14%. The changes in frailty among the patients receiving maintenance hemodialysis were categorized into three groups: moderate frailty worsening group ( n=64), frailty improvement group ( n=110), and stable pre-frailty group ( n=38). The average probabilities of patients belonging to each latent class were 0.948, 0.938, and 0.950, respectively. Age, gender, body mass index, anemia, continuing to work after illness onset, and comorbidities were identified as influencing factors of frailty trajectory changes in these patients (all P<0.05) . Conclusions:There are three types of frailty trajectory changes in patients receiving maintenance hemodialysis from the start of dialysis to 12 months of regular dialysis. Targeted interventions can be implemented based on the identified influencing factors.
