Real experience and needs of lymphoma patients during CAR-T therapy: a qualitative study
10.3760/cma.j.cn115682-20231218-02655
- VernacularTitle:淋巴瘤患者CAR-T治疗期间真实体验及需求的质性研究
- Author:
Lei DONG
1
;
Fengyang HU
;
Chenyang GUAN
;
Ting LI
;
Jin HAN
;
Haoyu ZHANG
;
Mingzhi ZHANG
Author Information
1. 郑州大学第一附属医院肿瘤科（河南省淋巴瘤诊疗中心），郑州 450000
- Keywords:
lymphoma;
CAR-T therapy;
Experience;
Need
- From:
Chinese Journal of Modern Nursing
2024;30(22):3020-3024
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the real experience and needs of lymphoma patients during chimeric antigen receptor T cell (CAR-T) therapy, so as to provide guidance for developing nursing intervention strategies.Methods:The phenomenological research method was used to conduct semi-structured interviews with 13 lymphoma patients receiving CAR-T therapy, and the interview data was analyzed using the Colaizzi 7-step analysis method.Results:Three themes were extracted, including diverse symptom perception (systemic symptoms such as fever and fatigue, as well as multiple system symptoms such as breathing, digestion, and nerves), complex emotional experience interweaving (coexistence of hope and doubt, changes and loss of environmental adaptability, and a variety of negative emotions), and urgent social needs (treatment related information needs, desire for medical and nursing staff's attention and help, family emotional support, and home rehabilitation continuing care) .Conclusions:Lymphoma patients experience significant physical and mental pain during CAR-T therapy. Medical and nursing staff should provide patients with comprehensive support to help them identify and improve physical discomfort symptoms, reduce psychological burden, meet physical and mental needs, and promote disease recovery.
