Based on"gut-joint axis",to explore new progress of TCM-intestinal flora interaction in treatment of autoimmune arthritis
10.3969/j.issn.1000-484X.2024.11.033
- VernacularTitle:基于"肠-关节轴"探讨中药-肠道菌群互作治疗自身免疫性关节炎研究新进展
- Author:
Jie CHEN
1
;
Jingbo ZHAI
;
Changlong LYU
;
Xiaodong LYU
Author Information
1. 辽宁中医药大学,沈阳 110847
- Keywords:
Gut-joint axis;
Traditional Chinese medicine;
Intestinal flora;
Autoimmune arthritis
- From:
Chinese Journal of Immunology
2024;40(11):2434-2439
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal flora can mediate intestinal inflammation to the joint site through the"gut-joint axis",activate local or systemic immune response,and cause joint inflammation and injury.Traditional Chinese medicine(TCM)has unique advantages in the treatment of autoimmune diseases.Recent studies have shown that the interaction between TCM and intestinal flora in the mucosal immune system is closely related to the occurrence and development of autoimmune diseases.Therefore,the possible therapeutic mechanism of the interaction of TCM and intestinal flora in autoimmune arthritis is discussed in this paper,with the view of"gut-joint axis",in order to bring new ideas for clinical prevention and treatment.
