Latest research progress in application of single-cell transcriptome sequencing technology in autoimmune diseases
10.3969/j.issn.1000-484X.2024.10.034
- VernacularTitle:单细胞转录组测序技术在自身免疫病中应用的最新研究进展
- Author:
Jinmei SUN
1
;
Chunwei SHI
;
Guilian YANG
;
Wentao YANG
;
Chunfeng WANG
Author Information
1. 吉林农业大学动物医学院,动物科学技术学院,吉林省重点实验室,动物微生态制剂工程研究中心,动物生产及产品质量安全教育部重点实验室,长春 130118
- Keywords:
Single-cell RNA sequencing;
Autoimmune disease;
Research progress
- From:
Chinese Journal of Immunology
2024;40(10):2219-2222,2228
- CountryChina
- Language:Chinese
-
Abstract:
Single-cell RNA sequencing technology takes a single cell as research object,counts and analyzes the gene expres-sion level of each transcript and heterogeneity between cells.This technology makes up for the defects of traditional sequencing techno-logy to some extent.Autoimmune disease is the damage or dysfunction of autotissue cells caused by autoimmune tolerance or abnormal regulation of autoimmunity cells.In this paper,the research results on application of single-cell RNA sequencing technology in autoim-mune disease in recent years are reviewed,which provides valuable clues for early realization of precise medical treatment.
