Decision-making experience and needs of patients in clinical trials of neoadjuvant immunotherapy for lung cancer: a qualitative study
10.3760/cma.j.cn115682-20230908-00970
- VernacularTitle:肺癌患者参与新辅助免疫治疗临床试验的决策体验与需求的质性研究
- Author:
Shujun XING
1
;
Jun'e LIU
;
Shuhang WANG
;
Dawei WU
;
Hong FANG
;
Yu TANG
;
Ning LI
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院，药物临床试验研究中心，北京 100021
- Keywords:
Lung neoplasms;
Neoadjuvant therapy;
Immunotherapy;
Clinical trial;
Decision-making experience;
Qualitative study
- From:
Chinese Journal of Modern Nursing
2024;30(16):2137-2142
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To deeply explore the decision-making experience of patients participating in clinical trials of neoadjuvant immunotherapy for lung cancer.Methods:Using the descriptive and qualitative research, 15 lung cancer patients who participated in clinical trials of neoadjuvant immunotherapy at the Cancer Hospital of the Chinese Academy of Medical Sciences were selected by purposive sampling from April 2021 to August 2022 for semi-structured in-depth interviews. Content analysis method was used for data analysis, summarization, and induction.Results:Three themes were extracted, namely decision-making information dilemma (insufficient or overloaded information, difficulty in understanding professional information, urgent need for decision-making information assistance), complex emotional experience (negative emotional experience, positive emotional experience), and hope for multi-party support (expecting psychological communication, hoping for family understanding, and longing for social recognition) .Conclusions:The decision-making experience of patients in clinical trials of neoadjuvant immunotherapy for lung cancer were summarized and described, which can help strengthen the understanding of the research team and medical and nursing staff on the live experience of such patients when making decisions, provide targeted decision support strategies, and promote good informed consent of patients.
