Research progress of TCR DNA vaccine in autoimmune diseases
10.3969/j.issn.1000-484X.2024.06.029
- VernacularTitle:TCR DNA疫苗在自身免疫病中的研究进展
- Author:
Junning ZHANG
1
;
Guangyu WANG
;
Minglin OU
;
Xianliang HOU
Author Information
1. 桂林医学院第二附属医院中心实验室,广西壮族自治区卫生健康委员会糖脂代谢病重点培育实验室,桂林 541199
- Keywords:
TCR;
TCR DNA vaccine;
Autoimmune diseases
- From:
Chinese Journal of Immunology
2024;40(6):1292-1296
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune disease(AID)is a disease in which the body loses tolerance to autoantigens and the immune system attacks its own tissues,resulting in organ and tissue damage and certain clinical manifestations.Studies have proved that pathogenic T cells can be selectively inhibited or killed by TCR vaccine in the treatment of AID,thus bringing broad application prospect.This pa-per briefly summarizes the research status of TCR vaccine in AID field,regarding action mechanism,related diseases and safety of TCR vaccine.
