Role of pseudogenes in proliferation,invasion and metastasis of hepatoma cells

VernacularTitle:伪基因在肝癌细胞增殖、侵袭和转移中的作用
Author: Wenjie GUO ¹ ; Fang LIU ; Na GAO ; Che CHEN ; Huiyuan CHU
Author Information

1. 甘肃中医药大学,兰州 730000
Keywords: Pseudogene; Liver cancer; Proliferation; Invasion; Metastasis
From: Chinese Journal of Immunology 2024;40(4):894-896,封3-封4
CountryChina
Language:Chinese
Abstract: Pseudogenes have long been regarded as fossilized,nonfunctional genomes that are evidence of human evolution.However,in recent years,pseudogenes have been found to play an important role in both physiological and pathological processes,especially in tumors,regulating occurrence and development of tumors in parental gene dependence and parental gene independence,including liver cancer.In this paper,we summarized research progress of pseudogenes and their roles in proliferation,apoptosis,inva-sion and metastasis of liver cancer cells,providing new ideas for treatment of liver cancer.