Myeloid-derived suppressor cells and hepatocellular carcinoma
10.3969/j.issn.1000-484X.2024.04.035
- VernacularTitle:髓源抑制性细胞与肝癌
- Author:
Junchi LIU
1
,
2
;
Yanru LI
Author Information
1. 吉林大学病理生物学教育部重点实验室,长春 130021
2. 吉林大学第一临床医学院,长春 130021
- Keywords:
MDSCs;
Hepatocellular carcinoma;
Immunosuppression;
Immunotherapy
- From:
Chinese Journal of Immunology
2024;40(4):880-887
- CountryChina
- Language:Chinese
-
Abstract:
Myeloid-derived suppressor cells(MDSCs)are a heterogeneous cell population in tumor immune microenviron-ment that can undergo amplification and aggregation in tumor patients and tumor-bearing animals,exerting immunosuppressive activi-ties.Recent studies have demonstrated the significant role of MDSCs in the occurrence,development and metastasis of liver cancer.This paper aims to review the research progress on MDSCs and hepatocellular carcinoma,exploring their involvement in hepatocellular carcinoma as well as potential therapeutic strategies.
