The role of dietary fiber in intestinal rehabilitation for patients with ultra-short bowel syndrome: a clinical study
10.3760/cma.j.cn115822-20240102-00002
- VernacularTitle:膳食纤维在超短肠综合征肠康复治疗中的作用研究
- Author:
Xin QI
1
;
Yufei XIA
;
Sirui LIU
;
Xuejin GAO
;
Li ZHANG
;
Xinying WANG
Author Information
1. 南京大学医学院附属金陵医院 普通外科研究所，南京 210002
- Keywords:
Ultra-short bowel syndrome;
Dietary fiber;
Intestinal rehabilitation treatment
- From:
Chinese Journal of Clinical Nutrition
2024;32(4):217-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the role of dietary fiber in the intestinal rehabilitation for patients with ultra-short bowel syndrome.Methods:This study included 34 inpatients diagnosed with ultra-short bowel syndrome in the General Surgery Department of the Eastern Theater General Hospital of the People's Liberation Army from January 2012 to October 2023. Patients were grouped based on whether they received intestinal rehabilitation and whether dietary fiber was added to the treatment plan, and were divided into three groups: nutritional therapy group (11 cases), growth hormone + glutamine intestinal rehabilitation treatment group (10 cases) and growth hormone injection + glutamine + dietary fiber intestinal rehabilitation treatment group (13 cases). The therapeutic regimen and its changes, pre- and post-treatment parameters of hematology, nutrition, intestinal absorption, fecal consistency, and quality of life were recorded and compared, and the impact of different treatment regimens on clinical outcomes was analyzed.Results:Compared with nutrition treatment group and growth hormone + glutamine intestinal rehabilitation treatment group, growth hormone injection + glutamine + dietary fiber intestinal rehabilitation treatment group, the increase of enteral nutritional fluid, the decrease of parenteral nutritional energy, the increase of intestinal moisture absorption, the decrease of defecation times and the appreciation of hemoglobin were significantly increased, and the difference was statistically significant ( P<0.05). At the same time, the levels of insulin-like growth factor 1 and insulin-like growth factor binding protein were significantly increased after treatment ( P<0.01). Conclusions:Nutritional support combined with intestinal rehabilitation can significantly improve the nutritional status and intestinal absorption rate of ultra-short bowel syndrome patients. The use of dietary fiber in the intestinal rehabilitation regimen for ultra-short bowel syndrome patients yields more significant benefits, as evidenced by improved clinical outcomes.
