Effect of oral immunotherapy with donor human milk on feeding tolerance in very low birth weight premature infants
10.3760/cma.j.cn115822-20240319-00053
- VernacularTitle:捐赠母乳口腔免疫疗法对极低出生体重早产儿喂养耐受的影响
- Author:
Xiaoxiao ZHANG
1
;
Yang QIN
;
Xu GAO
;
Jingjing YU
;
Guiran BIAN
;
Wenhuan CUI
;
Juan LI
;
Guifang LI
Author Information
1. 沧州市人民医院新生儿科，沧州 061000
- Keywords:
Premature infants with very low birth weight;
Donor human milk;
Oral immunotherapy;
Feeding intolerance in premature infants
- From:
Chinese Journal of Clinical Nutrition
2024;32(3):156-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of oral immunotherapy with donor human milk on feeding tolerance in premature infants with very low birth weight.Methods:A total of 94 extremely low birth weight preterm infants admitted to the neonatal Intensive Care Unit of Cangzhou People's Hospital from August 2022 to February 2024 were selected, These infants were randomized at 1:1 into 2 groups (47 cases each) using random number method. The control group were given oral 0.9% sodium chloride (oral drip), while the experimental group were given donor human milk (oral drip). General information were collected, including gender, delivery method, twins or not, small for gestational age or not, birth weight, gestational age, intestinal feeding of dairy products, and so on. Total intestinal feeding time, length of hospital stay and feeding intolerance were compared between groups.Results:The total intestinal feeding time and length of hospital stay were significantly shorter in the experimental group compared with the control group ( P<0.05). The incidence of feeding intolerance in the experimental group was also lower than that in the control group ( P<0.05). Conclusion:Oral immunotherapy with donor human milk can improve the feeding tolerance in premature infants with very low birth weight and shorten the hospital stay.
