The impact of central obesity on breast cancer risk and the significance of dietary factors
10.3760/cma.j.cn115822-20240205-00022
- VernacularTitle:中心性肥胖对乳腺癌发生风险的影响及膳食因素作用
- Author:
Yu ZHANG
1
;
Chunwei LI
;
Yongchao WANG
;
Yuanyuan BAO
;
Qi LI
;
Lin LI
;
Yi PANG
;
Chunli GUO
;
Yuchen FAN
;
Xiangchao MENG
;
Kang YU
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院临床营养科，北京 100730
- Keywords:
Breast cancer;
Central obesity;
Dietary factors
- From:
Chinese Journal of Clinical Nutrition
2024;32(2):65-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of central obesity on the risk of breast cancer and the possible role of dietary factors in its prevention.Methods:This study is a case-control study including a total of 212 participants, of whom 63 were with breast cancer, 71 were with breast nodules, and 80 were healthy controls. We used bioelectrical impedance analysis to measure body composition,and adopted the food frequency questionnaire to investigate dietary intake of participants.Results:The visceral adipose tissue ( OR=1.03, 95% CI: 1.003 to 1.077) and trunk fat mass ( OR=1.470, 95% CI: 1.104 to 2.184) were independently associated with the increased risk of breast cancer. Dietary patterns characterized by low dietary intake of beans and dairy products ( OR=1.300, 95% CI: 1.044 to 1.619) and high intake of cereals and red meat ( OR=2.254, 95% CI: 1.705 to 2.982) will increase the risk of breast cancer. Moreover, high meat intake ( β=0.268, 95% CI: 0.034 to 0.503) would advance the accumulation of visceral fat, while high bean intake ( β=-0.485, 95% CI: -0.865 to -0.104) would inhibit. Conclusions:Central obesity is an independent risk factor for breast cancer. Insufficient intake of beans and excessive intake of red meat are identified as factors that can exacerbate central obesity in breast cancer patients.
