Research progress on the effects of propofol on tumor growth and metastasis mechanism
10.12092/j.issn.1009-2501.2024.09.010
- VernacularTitle:丙泊酚对肿瘤生长和转移机制影响的研究进展
- Author:
Baowei JIN
1
;
Kai WANG
;
Jianrong GUO
Author Information
1. 绍兴市人民医院麻醉科,绍兴 312000,浙江
- Keywords:
propofol;
tumor;
transfer mecha-nism;
passage
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(9):1042-1048
- CountryChina
- Language:Chinese
-
Abstract:
Propofol,as a widely used intravenous anesthetic,has been found to have the potential of anti-tumor growth and metastasis in recent years.At present,the research on the mechanism of pro-pofol inhibiting tumor growth and metastasis is still relatively limited.In this paper,we summarize the recent studies on the role of propofol in inhibiting tumor growth and metastasis and its possible mo-lecular mechanisms,such as regulating specific sig-naling pathways or key molecules,and interacting with other molecules.At the same time,the appli-cation of propofol,including the optimization of ad-ministration route and dose,as well as the possibili-ty of being an adjunct therapy to radiotherapy and chemotherapy,was analyzed,and the recent stud-ies on the mechanism of propofol inhibiting tumor growth and metastasis were reviewed,providing a reference for further exploration of the application and research direction of propofol in clinical anti-tu-mor growth and metastasis therapy.
