Clinical research progress of esketamine application within the spinal canal

VernacularTitle:椎管内应用艾司氯胺酮的临床研究进展
Author: Yufeng SUN ¹ ; Xiaolin YANG ; Ying DING ; Yanrong LV ; Hongwei WU ; Chun YANG
Author Information

1. 南通大学附属如皋医院(如皋市人民医院)麻醉科,如皋 226500,江苏
Keywords: esketamine; spinal canal; analgesia; antidepressant
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2024;29(7):826-830
CountryChina
Language:Chinese
Abstract: Esketamine,which was recently intro-duced in China,is a type of intravenous general an-esthetic that is widely used in clinical practice for general anesthesia and anti-depression therapy.Studies have found that esketamine can be safely used to intrathecally produce analgesic,sedative,and anti-depressive effects at subanesthetic doses.This review summarizes the mechanism of action,safety,adverse reactions,and various clinical appli-cations of esketamine intrathecally,so as to pro-vide relevant references for further research.