Effects of cognitive behavioral therapy in elderly patients with depression: a Meta-analysis
10.3760/cma.j.cn115682-20230703-02613
- VernacularTitle:认知行为疗法对老年抑郁症患者干预效果的Meta分析
- Author:
Ye MAO
1
;
Yubiao KANG
;
Tian TIAN
;
Dan FANG
;
Xinyi YOU
;
Junjie TAO
;
Ye WANG
;
Jiali SUN
;
Bei WANG
;
Jianing LI
Author Information
1. 南京中医药大学护理学院，南京 210023
- Keywords:
Aged;
Depression;
Meta-analysis;
Cognitive behavioral therapy
- From:
Chinese Journal of Modern Nursing
2024;30(2):153-160
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the effect of cognitive behavioral therapy (CBT) in elderly patients with depression.Methods:The randomized controlled trials on the effect of CBT in elderly patients with depression, published until December 15, 2022, were searched in PubMed, CINHAL, Cochrane Library, China Biology Medicine, China National Knowledge Infrastructure, WanFang Data, and VIP. Two researchers independently screened the literature, extracted data, and used the revised Cochrane risk of bias tool for randomized trials (ROB 2.0) to evaluate the quality of the included studies. Statistical analysis was conducted using Stata 16.0, and the quality of evidence was rated using Appraisal of Guidelines for Research and Evaluation (GRADE) predictor software.Results:A total of 11 randomized controlled trials were included, with a total of 833 elderly patients with depression. Randomized effect models were used to analyze outcome indicators such as depression, anxiety, and quality of life by combining effect quantities. Meta-analysis and GRADE evidence quality showed that compared to the control group, medium quality evidence showed that CBT could relieve depression in elderly depression patients with a statistical difference [ SMD=-1.58, 95% CI (-2.16, -0.99), P<0.05]. Low quality evidence suggested that CBT could alleviate anxiety in elderly depression patients also with a statistical difference [ SMD=-2.25, 95% CI (-4.04, -0.47), P<0.05]. Very low quality evidence indicated that CBT did not significantly improve the quality of life in elderly depression patients compared to conventional or pharmacological treatment [ SMD=-0.09, 95% CI (-2.07, 1.88), P>0.05] . Conclusions:Existing evidence suggests that CBT can alleviate depression and anxiety in elderly depression patients, but its improvement in quality of life is not yet significant. Treatment feedback and forms of CBT may become a research focus in recent years on intervention for elderly depression patients.
