Effects of different intensity of high frequency repetitive transcranial magnetic stimulation on upper limb function in patients with early post-stroke
10.3969/j.issn.1001-1242.2024.09.009
- VernacularTitle:不同强度的高频重复经颅磁刺激对脑梗死早期患者上肢功能的影响
- Author:
Caifeng FU
1
;
Chao GAO
;
Mengjiao LIU
Author Information
1. 青岛大学附属青岛市中心医院康复医学科,山东省青岛市,266042
- Keywords:
cerebral infarction;
high-frequency repetitive transcranial magnetic stimulation;
upper limb function
- From:
Chinese Journal of Rehabilitation Medicine
2024;39(9):1304-1309
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of high-frequency repetitive transcranial magnetic stimulation(HF-rTMS)of different intensities on the recovery of upper limb motor dysfunction in patients during the early recovery stage of cerebral infarction. Method:Sixty patients with cerebral infarction at early recovery stage were randomly divided into the HF-rT-MS 80％RMT group,the HF-rTMS 100％RMT group and the sham stimulation group,with 20 patients in each group.All three groups were also given basic treatment(medication and routine rehabilitation training).Be-fore and after 4 weeks treatment,the Fugl-Meyer Assessment-Upper extremity(FMA-UE)and Modified Barth-el Index(MBI),the latency of motor evoked potential(MEP).central motor conduction time(CMCT)and blood flow velocity of the ipsilateral middle cerebral artery(MCA)were recorded. Result:Before treatment,there were no significant differences in FMA-UE score,MBI score,MEP latency,CMCT and the blood flow velocity of MCA among the three groups(P＞0.05).After four weeks of treatment,the above indicators of the three groups were significantly higher than those before treatment(P＜0.05).More-over,the improvement of the indicators in the 80％RMT group and 100％RMT group were significantly higher than those in the sham stimulation group(P＜0.05).Except for MBI score,the improvement in all indicators in the 100％RMT group were the most significant(P＜0.05). Conclusion:HF-rTMS can improve upper limb function and activity of daily living during the early recovery stage of cerebral infarction.Compared with 80％RMT,100％RMT HF-rTMS has more advantages in improv-ing function,motor nerve excitability and cerebral blood flow.
