Specific modulatory effects of different network-based transcranial direct current stimulation on gait char-acteristics in healthy adults
10.3969/j.issn.1001-1242.2024.05.006
- VernacularTitle:不同脑网络经颅直流电刺激方案对健康成年人步态特征的特异性调控效果研究
- Author:
Xiaofan FENG
1
;
Rong ZHOU
;
Jiaojiao LV
Author Information
1. 上海体育大学,运动健身科技省部共建教育部重点实验室,上海市,200438
- Keywords:
gait speed;
gait variability;
transcranial direct current stimulation;
brain network modulation
- From:
Chinese Journal of Rehabilitation Medicine
2024;39(5):647-654
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop three tDCS protocols based on the gait-related brain networks:the frontoparietal net-work(FPN),the dorsal-attention network(DAN),and the default network(DN),with the aim of specifical-ly modulating gait speed and gait variability and improving walking function. Method:In this study,healthy adults were recruited and randomly divided into 3 groups receiving different stimulation protocols:simultaneously enhancing the excitability of FPN and suppressing the excitability of DN(i.e.,FPN+/DN-tDCS),enhancing the excitability of DAN and suppressing the excitability of DN(i.e.,DAN+/DN-tDCS),and sham stimulation(Sham group).Normal,fast and dual-task gait tests were performed immediately before/after electrical stimulation,and spatiotemporal parameters and variability indicators of gait were collected.Two-way repeated measures ANOVA was used to assess the effects of three stimulation on gait characteristics under different conditions. Result:A total of 72 subjects were included in this study,64 of whom completed all tests.There were no significant interaction effects observed on gait spatiotemporal parameters in three conditions(normal,fast,dual-task walking conditions)and gait variability in normal walking between pre-and post-intervention assessments.In the fast gait task,there were significant interaction effects observed for stride length variability(F=3.671,P=0.031)and double support time variability(F=3.879,P=0.026).In the dual-task gait task,there were signif-icant interaction effects observed for stride width variability(F=3.940,P=0.025),gait speed variability(F=3.936,P=0.025),and double support time variability(F=4.913,P=0.011). Conclusion:The DAN+/DN-tDCS protocol were effective in reducing gait variability and improving gait stabili-ty during complex tasks in healthy adults.However,the FPN+/DN-tDCS protocol did not specifically improve gait speed under different conditions.
