MRI-based quantitative analysis of paraspinal muscle characteristics in patients with osteoporotic ver-tebral compression fractures
10.3969/j.issn.1004-406X.2024.06.05
- VernacularTitle:基于MRI的骨质疏松椎体压缩骨折患者椎旁肌特征定量分析研究
- Author:
Zezheng CHEN
1
,
2
;
Fangyong WANG
;
Wenjie ZHANG
Author Information
1. 首都医科大学康复医学院 100069 北京市
2. 中国康复研究中心北京博爱医院脊柱脊髓外科 100069 北京市
- Keywords:
Osteoporotic vertebral compression fractures;
Paraspinal muscle;
Fatty infiltration;
Vertebral bone quality score;
Magnetic resonance imagine
- From:
Chinese Journal of Spine and Spinal Cord
2024;34(6):595-601,619
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To compare and analyze the MRI characteristics and fatty infiltration(FI)of the lum-bar spine in patients with and without osteoporotic vertebral compression fracture(OVCF)to explore their rela-tionships with fracture.Methods:46 patients with OVCF(70.67±11.99 years old;11 males,35 famales)were retrospectively analyzed,and 46 age-(70.76±5.40)and sex-(11 males,35 famales)matched osteoporotic pa-tients without OVCF were taken as the control group.Paravertebral muscle FI,cross-sectional area(CSA),and vertebral bone quality(VBQ)score were measured on lumbar MRI.Independent samples t-test was used to compare the differences between the OVCF group and the control group,and regression analysis was per-formed to explore the risk factors for the development of OVCF.Results:Patients in the OVCF group had significantly higher VBQ scores(P<0.05)and significantly higher paravertebral muscle FI(P<0.05)than those in the control group.There was no significant difference in CSA of paravertebral muscles between the two groups.VBQ score(OR=1.963,P<0.01)and FI of paravertebral muscles represented by L4(OR=1.203,P<0.01)were the independent risk factors for OVCF.Conclusions:The MRI parameters of lumbar spine in patients with OVCF had greater VBQ scores and paravertebral muscle FI compared with the osteoporotic patients without OVCF;VBQ scores and paravertebral muscle FI are the independent risk factors for OVCF,and at-tentions should be paid to improve paravertebral muscle functions in the meantime of preventing OVCF.