MRI classification of extraprostatic extension of prostate cancer for predicting positive surgical margin after laparoscopic radical prostatectomy
10.13929/j.issn.1672-8475.2024.10.008
- VernacularTitle:前列腺癌包膜外侵犯MRI分型预测腹腔镜根治性前列腺切除术后切缘阳性
- Author:
Chao ZHONG
1
,
2
;
Junguang WANG
;
Kecheng ZHANG
;
Jing WANG
;
Xiaohui ZHANG
;
Hong ZHANG
Author Information
1. 浙江大学医学院,浙江 杭州 310030
2. 宁波市泌尿肾病医院放射科,浙江 宁波 315000
- Keywords:
prostatic neoplasms;
prostatectomy;
magnetic resonance imaging
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(10):602-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of MRI classification of extraprostatic extension(EPE)of prostate cancer(PCa)for predicting positive surgical margin after laparoscopic radical prostatectomy(LRP).Methods Prostate MRI data of 114 PCa patients with stage T3a who underwent LRP were retrospectively analyzed.The patients were divided into type Ⅰ(n=14),Ⅱ(n=50)and Ⅲ group(n=50)according to EPE location,also into positive margin group(n=58)and negative margin group(n=56)according to postoperative pathology.Then clinical,imaging,surgical and pathological data were compared among type Ⅰ—Ⅲ groups and between positive and negative margin groups.The indicators being significantly different between positive and negative margin groups were included in multivariate logistic regression analysis to screen the independent impact factors of positive margin of stage T3a PCa after LRP.Results Significant differences of patients'age,prostate-specific antigen(PSA),tumor location and positive surgical margin rate were found among type Ⅰ—Ⅲ groups(all P＜0.05).Positive surgical margin rate in type Ⅲ group was 68.00%(34/50),higher than that in type Ⅰ(14.29%[2/14])and Ⅱ group(44.00%[22/50])(both P＜0.05).Meanwhile,significant differences of PSA,the proportion of positive puncture needles and EPE MRI classification of PCa were found between positive and negative margin groups(all P＜0.05),among which the proportion of positive puncture needles and EPE MRI classification of PCa were both independent impact factors of positive margin of stage T3a PCa after LRP(both P＜0.05).Conclusion MRI classification of PCa-EPE could be used to predict positive surgical margin after LRP.Positive surgical margin after LRP tended to occur in PCa with MRI type Ⅲ EPE.
