Spectral CT multi-parameter imaging for preoperative predicting lymph node metastasis of gastric cancer
10.13929/j.issn.1672-8475.2024.10.007
- VernacularTitle:能谱CT多参数成像术前预测胃癌淋巴结转移
- Author:
Yusong CHEN
1
,
2
,
3
,
4
;
Yiyang LIU
;
Shuai ZHAO
;
Mengchen YUAN
;
Weixing LI
;
Yaru YOU
;
Yue ZHENG
;
Songmei FAN
;
Jianbo GAO
Author Information
1. 郑州大学第一附属医院放射科,河南 郑州 450052
2. 河南省医学影像国际联合实验室,河南 郑州 450052
3. 河南省消化肿瘤影像重点实验室,河南 郑州 450052
4. 河南省CT影像重点实验室,河南 郑州 450052
- Keywords:
stomach neoplasms;
lymphatic metastasis;
tomography,X-ray computed;
spectral imaging
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(10):596-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of spectral CT multi-parameter imaging for preoperative predicting lymph node metastasis(LNM)of gastric cancer.Methods Totally 136 patients with gastric adenocarcinoma were retrospectively enrolled.The patients were further divided into LNM group(n=74)and non-LNM group(n=62)according to postoperative pathological findings of lymph nodes status.Clinical data,conventional CT findings and spectral CT parameters were compared between groups.Factors being significant different between groups were included in multivariate logistic regression analysis to screen independent predictors of gastric cancer LNM.Clinical+conventional CT model(model 1),spectrum CT model(model 2)and combined model(model 3)were constructed based on the above independent predictors,respectively.Receiver operating characteristic curve was drawn,and the area under the curve(AUC)was calculated to evaluate the efficacy of each model for preoperative predicting LNM of gastric cancer.Results CT-N stage,CT-T stage,70,100 and 140 keV CT valuestumor at arterial phase(AP),arterial enhancement fraction(AEF)and normalized iodine concentration at venous phase(NICVP)were all independent predictors of gastric cancer LNM(all P＜0.05).AUC of model 3 was 0.846,higher than that of model 1 and model 2(AUC=0.767,0.774,Z=-0.368,-2.373,both P＜0.05)for preoperative predicting LNM of gastric cancer,while the latter two were not significantly different(Z=-0.152,P=0.879).Conclusion Spectral CT multi-parameter imaging could effectively predict LNM of gastric cancer preoperatively.
