TIPS combined with catheter-directed thrombolysis and percutaneous transhepatic portal vein catheterization thrombolysis for acute non-cirrhotic non-neoplastic portal vein thrombosis
10.13929/j.issn.1672-8475.2024.10.003
- VernacularTitle:TIPS联合导管接触溶栓与经皮经肝门静脉穿刺置管溶栓治疗急性非肝硬化非肿瘤性门静脉血栓
- Author:
Jie JI
1
;
Bifei WU
;
Lele YAN
;
Penghua LYU
;
Weizhong ZHOU
;
Fu'an WANG
Author Information
1. 苏北人民医院介入放射科,江苏 扬州 225001
- Keywords:
venous thrombosis;
thrombolytic therapy;
portasystemic shunt,transjugular intrahepatic;
catheters,indwelling
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(10):583-587
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comparatively observe the value of TIPS combined with catheter-directed thrombolysis and percutaneous transhepatic portal vein catheterization thrombolysis for acute non-cirrhotic non-neoplastic portal vein thrombosis(PVT).Methods Twenty-five patients with acute non-cirrhotic non-neoplastic PVT were retrospectively enrolled and clustered into TIPS group(n=17,underwent TIPS combined with catheter-directed thrombolysis)and liver puncture group(n=8,underwent percutaneous transhepatic portal vein catheterization thrombolysis)according to the access of thrombolysis.The technical success rate,duration of catheter-directed thrombolysis,complications within 7 days,as well as portal vein patency 3 months after treatment,Child-Pugh grading of liver function and occurrence of hepatic encephalopathy(HE)were recorded and compared between groups.Results The technical success rates were both 100%in 2 groups.There was no significant difference of the duration of catheter-directed thrombolysis between groups(P＞0.05).The thrombolytic effect in TIPS group was better than that in liver puncture group(P＜0.05).No significant difference of the occurrence of bleeding within 7 days was found between groups(P＞0.05).After 3 months'follow-up,the degree of portal vein patency in TIPS group was higher than that in liver puncture group(P＜0.05).No significant difference of Child-Pugh grading of liver function nor occurrence of HE was found between groups(both P＞0.05).Conclusion Both TIPS combined with catheter-directed thrombolysis and percutaneous transhepatic portal vein catheterization thrombolysis were effective for treating acute non-cirrhotic non-neoplastic PVT,and the thrombolytic effect of the former was better than the latter.
