Ablation ranges of single and double needle microwave ablation of pig lung in vivo
10.13929/j.issn.1672-8475.2024.08.011
- VernacularTitle:单针与双针微波消融活体猪肺范围
- Author:
Na KOU
1
;
Fuliang LUO
;
Hongli LI
;
Jun TENG
;
Mengfei ZHAO
;
Ronghua JIANG
;
Mengyuan ZHAO
;
Hongwu WANG
Author Information
1. 北京中医药大学东直门医院呼吸科,北京 100700
- Keywords:
ablation techniques;
animal experimentation;
lung;
pig
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(8):491-494
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare ablation ranges of single and double needle microwave ablation(MWA)of pig lung in vivo.Methods Five healthy Bama miniature pigs were enrolled.Single needle(single needle group)and parallel double needle MWA(double needle group)were performed successively on bilateral lungs,respectively.Adverse event during MWA was evaluated according to common terminology criteria for adverse events(CTCAE).The long diameter(D1CT),short diameter(D2CT),longitudinal diameter(D3CT)and volume(V)of ablation foci were measured and calculated based on CT images immediately after MWA,whereas D1,s D2s and sphericity of ablation foci were also obtained based on specimen and compared between groups.Results D1CT,D2CT,D3CT and V,as well as D1S,D2S and sphericity of ablation foci in single needle group were all significantly smaller than those in double needle group(all P＜0.01).Mild pneumothorax(CTCAE grade 1)was found in 1 pig(1/5,20.00%)in single needle group,while mild pneumothorax and pulmonary hemorrhage(both CTCAE grade 1)occurred in 1 pig(1/5,20.00%)in double needle group.No other adverse event was observed.Conclusion Compared with single needle MWA,double needle MWA of pig lung in vivo resulted larger ablation range and more spherically shaped ablation foci.
