TACE combined with propranolol for treating giant infantile hepatic hemangioma
10.13929/j.issn.1672-8475.2024.08.001
- VernacularTitle:TACE联合普萘洛尔治疗巨大婴儿肝血管瘤
- Author:
Weiwei QI
1
;
Song WANG
;
Deng PAN
;
Xiaoli CHEN
;
Shiyu LI
;
Chuangao YIN
Author Information
1. 安徽省儿童医院影像科,安徽 合肥 230054
- Keywords:
liver;
hemangioma;
infant;
chemoembolization,therapeutic
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(8):449-452
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and safety of TACE combined with propranolol for treating giant infantile hepatic hemangioma(IHH).Methods Ten infants with giant IHH who underwent TACE combined with propranolol were retrospectively enrolled.The technical success rate,complications and recurrence were recorded.The therapeutic effect was evaluated according to clinical symptoms and changes of IHH volume before and 6 months after TACE.Results Totally 15 times of TACE were successfully performed in 10 infants,with technical success rate of 100%.Bleomycin-lipiodol emulsion+poly(vinyl alcohol)(PVA)+coil embolization were performed in 3 cases,while bleomycin-lipiodol emulsion+PVA embolization were performed in 7 cases.Complications of TACE included subcutaneous hematoma around the puncture site in 1 case and transient hypothermia within 24 h after TACE in 2 cases,all alleviated after symptomatic treatments.No other complication occurred.Six months after the last TACE,significantly effective was observed in 9 cases(9/10,90.00%),while effective was noticed in 1 case(1/10,10.00%),with total therapeutic effective rate of 100%.No serious complication such as gallbladder necrosis,liver necrosis,death,nor recurrence of hepatic hemangioma occurred during follow-up.Conclusion TACE combined with propranolol was effective and safe for treating giant IHH.
