Extracellular volume fraction based on CT for predicting macrotrabecular-massive hepatocellular carcinoma
10.13929/j.issn.1672-8475.2024.07.011
- VernacularTitle:基于CT细胞外间隙容积分数预测粗梁-团块型肝细胞癌
- Author:
Jiale HANG
1
;
Wenjian WANG
;
Xin YANG
;
Xiuchun TIAN
;
Jianxiong FU
;
Jun SUN
;
Jing YE
;
Xianfu LUO
Author Information
1. 苏北人民医院,扬州大学附属苏北人民医院医学影像科,江苏 扬州 225001
- Keywords:
carcinoma,hepatocellular;
tomography,X-ray computed;
extracellular volume fraction
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(7):431-435
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of extracellular volume fraction(ECV)based on CT for predicting macrotrabecular-massive hepatocellular carcinoma(MTM-HCC).Methods Data of 23 MTM-HCC(MTM-HCC group)and 56 non-MTM-HCC(nMTM-HCC group)patients were retrospectively analyzed,and CT manifestations were compared between groups.CT values of abdominal aorta(P-CTabdominal aorta,E-CTabdominal aorta),tumors(P-CTtumor,E-CTtumor)and non-tumor liver parenchyma(P-CTliver,E-CTliver)in plain phase(P)and enhancement equilibrium phase(E)CT were measured,then ECV of tumors and liver parenchyma were calculated,and ECV-related parameters were compared between groups.Receiver operating characteristic curves were drawn,and area under the curve(AUC)was calculated to evaluate the predictive efficacy of ECV-related parameters for predicting MTM-HCC.Results No significant difference of CT manifestations was found between groups(all P＞0.05).E-CTtumor,Δltumor(absolute enhancement CT value of the tumor area)and ECVtumor in MTM-HCC group were all lower than those in nMTM-HCC group(all P＜0.01).The AUC of E-CTtumor,Δtumor and ECVtumor for predicting MTM-HCC was 0.74,0.77 and 0.87,respectively,and the AUC of ECVtumor was higher than that of E-CTtumor and Δtumor(Z=2.271,2.557,P=0.023,0.011).Conclusion ECV based on CT could be used to effectively predict MTM-HCC.
