Symptom cluster and sentinel symptoms in patients with primary liver cancer treated with TACE
10.3760/cma.j.cn115682-20230307-00852
- VernacularTitle:原发性肝癌TACE治疗患者症状群及前哨症状的调查
- Author:
Jianfeng ZHANG
1
;
Hongyan DUAN
;
Xia SHEN
;
Jie ZHANG
;
Jianwei JIANG
Author Information
1. 江南大学无锡医学院，无锡 214000
- Keywords:
Liver neoplasms;
Transcatheter arterial chemoembolization;
Symptom cluster;
Sentinel symptoms
- From:
Chinese Journal of Modern Nursing
2023;29(28):3884-3889
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the symptom clusters of patients during transcatheter arterial chemoembolization (TACE) treatment for primary liver cancer and to identify the sentinel symptoms within the symptom clusters.Methods:Using the convenient sampling method, a total of 170 patients with primary liver cancer who were admitted to the Interventional Department in Affiliated Hospital of Jiangnan University for TACE treatment from June 2022 to January 2023 were selected as research objects. From the day after TACE treatment to 4 days after surgery, M.D.Anderson Symptom Inventory-Chinese (MDASI-C) , The Symptom Module Specific to Primary Liver Cancer (TSM-PLC) and First Symptom Appearance Schedule were completed every day. Firstly, the principal component analysis method was used to determine the symptom clusters, and then the sentinel symptoms are determined based on the initial onset time of the symptoms within the cluster combined with the Apriori algorithm. A total of 170 questionnaires were distributed in this study, and 163 valid questionnaires were collected, with an effective response rate of 95.88% (163/170) .Results:A total of 5 symptom clusters were extracted, including upper gastrointestinal tract, post embolism, feeling of illness, emotion and liver function impairment. Nausea, pain, difficulty sleeping, and sadness were sentinel symptoms in the upper gastrointestinal tract, post embolism, feeling of illness and emotional symptom groups, respectively. No clear sentinel symptoms were observed in the symptom cluster of liver function impairment.Conclusions:Primary liver cancer patients have multiple symptom clusters during TACE treatment, and the determination of sentinel symptoms is of great significance in improving symptom management efficiency and nursing quality.
