Nomogram based on ultrasound for predicting residue of benign thyroid nodules after microwave ablation
10.13929/j.issn.1672-8475.2024.06.002
- VernacularTitle:基于超声列线图预测甲状腺良性结节微波消融后残留
- Author:
Hongbing WU
1
;
Baoqi LI
;
Yan LI
;
Weifeng ZHOU
;
Jinping WANG
Author Information
1. 安徽中医药大学第一附属医院超声医学科,安徽 合肥 230031
- Keywords:
thyroid nodule;
ablation techniques;
treatment outcome;
nomograms
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(6):325-328
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of nomogram obtained with multivariate logistic regression based on ultrasound for predicting residue of benign thyroid nodules after microwave ablation(MWA).Methods Totally 101 patients with 133 benign thyroid nodules who underwent ultrasound-guided MWA were retrospectively enrolled.The nodules were divided into residual group(n=21)and non-residual group(n=112)according to follow-up results of contrast-enhanced ultrasound(CEUS)1 month after MWA.The ultrasonic performances of nodules before MWA were compared between groups,and those being statistically different were included in a multivariate logistic regression model to identify the independent predictors for residue after MWA,and the model was then visualized as a nomogram.The discrimination of the nomogram for predicting residue after MWA was assessed with receiver operating characteristic curve and area under the curve(AUC),and its calibration was assessed with Hosmer-Lemeshow goodness-of-fit test.Results High ablation risk and nodules volume shown with ultrasound were both independent predictors of residue of benign thyroid nodules after MWA(both P＜0.05),indicating that benign thyroid nodules with high ablation risk(OR=17.637[2.528,123.019])and large volume(OR=1.297[1.155,1.457])had relatively higher risk of residue after MWA.AUC of the nomogram was 0.756 for predicting residue of benign thyroid nodules after MWA,while Hosmer-Lemeshow test showed good fit(P=0.401).Conclusion Benign thyroid nodules with high ablation risk and large volume shown with ultrasound had relatively high risk of residue after MWA,which could be predicted conveniently and effectively with the obtained nomogram.
