Impact of cold circulation liquid temperature on ablation focus morphology of microwave ablation for porcine liver in vitro
10.13929/j.issn.1672-8475.2024.05.009
- VernacularTitle:冷循环液温度对微波消融离体猪肝消融灶形态的影响
- Author:
Xia LUO
1
;
Ping HE
;
Xin YANG
;
Juying ZHANG
;
Qiong JIANG
;
Linli FENG
;
Hanmei LI
;
Xiaoqing TANG
;
You YANG
;
Jinhong YU
Author Information
1. 川北医学院附属医院超声科,四川 南充 637000
- Keywords:
ablation techniques;
animal experimentation;
porcine liver
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(5):294-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the impact of cold circulation liquid temperature on ablation focus morphology of microwave ablation(MWA)for in vitro porcine liver tissue.Methods Twenty in vitro fresh porcine liver blocks were randomly divided into ice water circulation group(group A)and normal temperature circulation group(group B),respectively.Ten target ablations in each subgroups in group A and group B,i.e.A1 and B1(50 W,1 min),A2 and B2(50 W,5 min),A3 and B3(60 W,1 min),A4 and B4(60 W,5 min),A5 and B5(70 W,1 min)as well as A6 and B6(70 W,5 min)subgroups were performed using different ablation power(50,60,70 W)and ablation time(1,5 min),respectively.Then the morphology indexes of ablation foci,including longitudinal diameter(LD),transverse diameter(TD),roundness index(RI)and volume(V)were compared between subgroups in group A and B,also among subgroups within group A and B.Results Under the same ablation power and time,LD of ablation foci in subgroups of group A were all smaller than those of group B(all P＜0.05).Significant differences of RI of ablation foci were found between A1 and B1,A2 and B2,A4 and B4,A5 and B5 as well as A6 and B6 subgroups(all P＜0.05),but not between A3 and B3 subgroups(P＞0.05).However,the main effect of cold circulation liquid temperature on ablation focus TD(F=1.125)nor V(F=3.332)was not significant(both P≥0.05).Under the same cold circulation liquid temperature,significant differences of the morphology indexes of ablation foci were detected between A1 and A2,A3 and A4 as well as A5 and A6 subgroups,also between corresponding subgroups in group B(all P＜0.05).Conclusion During MWA for in vitro porcine liver tissue under constant ablation power and time,taken ice water as the cold circulation liquid was benefit to ablation focus shaped spherically.With the extension of ablation time,the larger the ablation focus,the higher the RI.
