Anticoagulation alone and combining with intervention for treating severe cerebral venous thrombosis
10.13929/j.issn.1672-8475.2024.05.005
- VernacularTitle:抗凝与其联合介入方法治疗重症颅内静脉血栓形成
- Author:
Zhen XU
1
;
Hao HE
;
Yingge XU
;
Lei YAN
;
Song ZHANG
;
Ming ZHU
;
Yinyin WU
;
Shaofeng SHUI
Author Information
1. 郑州大学第一附属医院介入科,河南 郑州 450052
- Keywords:
cerebral veins;
intracranial thrombosis;
thrombolytic therapy;
thrombectomy
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(5):276-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare therapeutic efficacy of anticoagulation alone and combining with intervention for treating severe cerebral venous thrombosis(CVT).Methods Data of 65 severe CVT patients were retrospectively analyzed.The patients were divided into anticoagulation group(n=32)or combined group(n=33)according to therapeutic methods.The modified Rankin scale(mRS)score at admission and discharge,the prognosis of patients,vascular recanalization rate as well as incidence of complications during follow-up period were compared between groups.Results No significant difference of mRS scores at admission was found between groups(P＞0.05),while mRS scores of combined group were lower than of anticoagulation group at discharge(P＜0.05).The rate of good prognosis at discharge(84.85%vs.59.38%),6 months after discharge(87.88%vs.65.63%)and 12 months after discharge(93.94%vs.75.00%)in combined group were all higher than those in anticoagulation group(all P＜0.05).The vascular recanalization rate in combined group was higher than that in anticoagulant group(100%vs.75.00%,P＜0.05).At the end of follow-up,no significant difference of complication incidence was found between groups(15.15%vs.18.75%,P＞0.05).Conclusion For patients with severe CVT,anticoagulation combined with interventional therapy could significantly alleviate clinical symptoms and improve prognosis compared with anticoagulation alone.
