Comparison on prognosis of hepatocellular carcinoma patients with hepatitis B and hepatitis C after microwave ablation
10.13929/j.issn.1672-8475.2024.05.002
- VernacularTitle:对比乙型与丙型肝炎背景下肝细胞癌患者经微波消融治疗后预后
- Author:
Luo WANG
1
;
Jie YU
;
Yanchun LUO
;
Xiaoling YU
;
Jing ZHANG
;
Zhigang CHENG
;
Zhiyu HAN
;
Fangyi LIU
;
Ping LIANG
Author Information
1. 南开大学医学院,天津 300071
- Keywords:
carcinoma,hepatocellular;
ablation techniques;
hepatitis B;
hepatitis C;
prognosis
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(5):262-267
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comparatively explore the prognosis of hepatocellular carcinoma(HCC)patients with hepatitis B(HB)and hepatitis C(HC)after microwave ablation(MWA).Methods Data of 159 HCC patients with HB(HB-HCC)and 159 HCC patients with HC(HC-HCC)who received MWA treatment were retrospectively collected.The oncologic outcomes were compared between groups,the causes of death were analyzed,and the risk factors of overall survival(OS)in HCC patients after MWA were observed.Results The OS rate in HC-HCC group was lower than that in HB-HCC group(P=0.045),while no significant difference of disease free survival rate(P=0.095)nor cancer specific survival rate(P=0.180)was found between groups.Compared with HB-HCC group,HC-HCC group had higher risk of death due to complications related to liver cirrhosis(HR=2.339,P=0.043).Child-Pugh class B(HR=3.082,P＜0.001),hepatitis viral load＞500 IU/ml(HR=1.654,P=0.006)and the maximum diameter of lesion≥3.0 cm(HR=1.541,P=0.017)were all independent risk factors of OS in HCC patients after MWA.Conclusion Compared with HB-HCC patients,HC-HCC patients had shorter OS after MWA.
