Meta-analysis of risk factors for postoperative delirium in patients with colorectal cancer
10.3760/cma.j.cn115682-20221202-05817
- VernacularTitle:结直肠癌患者术后谵妄危险因素的Meta分析
- Author:
Yue LI
1
;
Xiaorong MAO
;
Hua GUAN
;
Haiyan WU
;
Qin MAO
;
Xiaocui ZOU
;
Yuanyuan PAN
;
Tingxin LI
Author Information
1. 电子科技大学附属医院·四川省人民医院老年护理单元，成都 611731
- Keywords:
Colorectal neoplasm;
Meta-analysis;
Postoperative delirium;
Risk factor
- From:
Chinese Journal of Modern Nursing
2023;29(27):3695-3702
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors for postoperative delirium in colorectal cancer patients based on Meta-analysis.Methods:A computer search was conducted on PubMed, Embase, Web of Science, Cochrane Library, CNKI, Wanfang, VIP and China Biology Medicine disc, and literatures on influencing factors of postoperative delirium of colorectal cancer published by each database until April 6, 2022 were selected. Two researchers independently screened the literature, extracted the data, and evaluated the quality of the literature using Newcastle-Ottawa Scale (NOS) . Stata 15.0 statistical software was used to conduct a Meta-analysis of the included literatures.Results:A total of 19 articles were included, including 5 295 patients. The Meta-analysis results showed that the combined odds ratio ( OR) values and 95% confidence interval (95% CI) of various factors for postoperative delirium in colorectal cancer patients were advanced age [1.10 (1.06-1.14) ] , male [2.29 (1.81-4.44) ] , alcohol abuse [3.14 (1.63-6.06) ] , preoperative physical condition grading (≥level 3) [1.47 (1.13-1.91) ] , comorbidities [1.59 (1.16-2.17) ] , history of mental illness [7.86 (4.57-13.54) ] , history of cerebrovascular disease [5.74 (3.78-8.72) ] , cognitive impairment [3.31 (1.20-9.08) ] , albumin [0.81 (0.66-0.99) ] , perioperative blood transfusion [2.29 (1.41-3.69) ] and C-reactive protein [2.24 (1.11-4.53) ] , all P<0.05. Conclusions:The risk factors for delirium in colorectal cancer patients after operation are old age, male, alcoholism, preoperative physical condition grading≥level 3, combined diabetes and other basic diseases, history of mental disease, history of cerebrovascular disease, cognitive dysfunction, low albumin, perioperative blood transfusion and elevated C-reactive protein.
