Safety and efficacy of domestically produced novel bioabsorbable vascular scaff old in the treatment of complex coronary artery lesions for 3 years
10.3969/j.issn.1004-8812.2024.09.005
- VernacularTitle:国产新型生物可吸收支架治疗复杂冠状动脉病变3年的安全性及有效性
- Author:
Deng-Shuang ZHOU
1
;
Qiong YOU
;
Hai-Liang MO
;
Zi-Jun WU
;
Yu-Biao LIN
;
Lu-Jun CHEN
;
Jun-Yu FAN
;
Yong-Jian LIN
;
Rui-Sheng ZHANG
;
Pei-Shan WAN
;
Wei-Guo ZHOU
;
Keng WU
Author Information
1. 广东医科大学附属医院冠心病专科,广东湛江 524200
- Keywords:
Bioabsorbable vascular scaffold;
Drug-eluting stent;
Percutaneous coronary intervention;
Coronary heart disease
- From:
Chinese Journal of Interventional Cardiology
2024;32(9):509-515
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and efficacy of novel bioabsorbable vascular scaffold(BVS)in the treatment of patients with complex coronary artery disease.Methods This was a retrospective,matched,single-center observational study.45 patients with coronary atherosclerotic cardiopathy received BVS treatment in the cardiovascular medicine department Department of the Affiliated Hospital of Guangdong Medical University from June 2020 to June 2021(BVS),and 45 patients treated with drug-eluting stents(DES)group were selected according to matching study requirements during the same period.Baseline,surgical,and follow-up data were compared between the two groups to evaluate safety and efficacy.The main measures of safety were:surgical time,intraoperative adverse events,etc.,and the end point of efficacy was target lesion failure(TLF),including cardiac death,target vessel myocardial infarction,and ischa-driven target lesion revascularization.Results A total of 90 patients were enrolled in this study,all of whom were followed up for at least 3 years.There were 20 cases of bifurcation lesions and 25 cases of diffuse long lesions in the two groups,and 50 cases of imaging were reviewed among the 90 patients.The proportion of stable coronary heart disease,history of diabetes,history of hypertension,history of smoking,pre-dilated balloon pressure and postoperative diastolic blood pressure in BVS group was higher than that in DES group,and the proportion of family history was lower than that in DES group(all P＜0.05).There were no statistically significant differences in the rates of cardiac death,target vessel myocardial infarction,and ischemia-driven revascularization of target lesions between the two groups(all P＞0.05).Binary Logistic regression model analysis showed that the diameter stenosis ratio of target lesions was an independent risk factor for intrastent restenosis(OR 2.786,95％CI 1.096-7.081,P=0.031).Conclusions Compared with traditional DES,BVS implantation has consistent safety and efficacy in the treatment of complex coronary artery disease within 3 years.The diameter stenosis ratio of target lesions was an independent risk factor for intrastent restenosis.
