The prospect and challenges of injectable hydrogel in the treatment of chronic heart failure
10.3969/j.issn.1004-8812.2024.08.006
- VernacularTitle:可注射水凝胶在慢性心力衰竭治疗中的前景与挑战
- Author:
Shu-Cheng LI
1
;
Bing-Chen GUO
;
Dian-Yu GAO
;
Bo WANG
;
Ying-Feng TU
Author Information
1. 哈尔滨医科大学附属第一医院心血管内科,黑龙江哈尔滨 150001
- Keywords:
Heart failure;
Interventional strategy;
Injectable hydrogel
- From:
Chinese Journal of Interventional Cardiology
2024;32(8):451-456
- CountryChina
- Language:Chinese
-
Abstract:
Heart failure is the leading cause of mortality in cardiovascular diseases and represents the ultimate common manifestation of most cardiovascular conditions,impacting over 60 million individuals globally.Currently,heart transplantation remains the standard treatment for heart failure patients.Adherence to fundamental pharmacotherapy can improve quality of life and extend survival time for heart failure patients.However,due to the complex mechanism of heart failure and numerous complications,the limitations of conventional heart failure treatment strategies in clinical work are gradually magnified.In recent years,interventional therapy has emerged as an innovative approach for managing heart failure,attracting significant attention and achieving substantial breakthroughs that offer new hope for affected individuals.Injectable hydrogel has garnered considerable interest in biomedicine due to its minimally invasive nature and capacity for efficient therapeutic drug delivery.In the context of chronic heart failure,injectable hydrogel finds application primarily in tissue regeneration,drug delivery,and immunotherapy.This review mainly describes the application and research progress of injectable hydrogel in the treatment of heart failure.