One-year outcomes of D-shant atrial shunt device for patients with heart failure with reduced ejection fraction
10.3969/j.issn.1004-8812.2024.08.003
- VernacularTitle:D-shant心房分流器用于射血分数降低的心力衰竭患者短期结果
- Author:
Yi-Wei WANG
1
;
Ping JIN
;
Meng-En ZHAI
;
Xin MENG
;
Yu-Xi LI
;
Yu MAO
;
Yuan-Zhang LIU
;
Jian YANG
;
Yang LIU
Author Information
1. 中国人民解放军空军军医大学第一附属医院心血管外科,陕西西安 710032
- Keywords:
Heart failure with reduced ejection fraction;
Percutaneous inter-atrial shunting;
Atrial shunt device;
Pulmonary capillary wedge pressure;
D-shant
- From:
Chinese Journal of Interventional Cardiology
2024;32(8):434-442
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical short-term outcomes of implanting D-shant atrial shunt device(aSD)in a single center for patients with heart failure with reduced ejection fraction(HFrEF).Methods From January 2022 to January 2023,a retrospective analysis was conducted on 12 patients with HFrEF who underwent percutaneous implantation of a D-shant aSD.We assessed cardiac chamber size and ventricular function using echocardiography,right heart catheterization measurements and patient clinical indicators were collected,follow up data of 12 months postoperative and pre-implantation D-shant were compared.The primary endpoint of the study was the cumulative occurrence of adverse cardiac,neurologic,or renal events during the follow-up period.Secondary endpoints were improvements in functional status included cardiac function,quality of life,and exercise capacity.Results All 12 patients underwent successful percutaneous inter-atrial shunting procedures using the D-shant.Postoperative immediately fluoroscopy and echocardiography confirmed accurate localization and patency of the atrial shunt devices in all cases.Postoperative hemodynamic assessment revealed a significant decrease in pulmonary capillary wedge pressure[(29.8±3.4)mmHg vs.(17.8±0.8)mmHg,P＜0.001].During 12 months follow-up,the cumulative adverse event rate was 8.3％(one patient received a heart transplant),a significant reduction in left atrial diameter from(65.8±6.5)mm to(48.0±4.5)mm(P＜0.001)was observed.Furthermore,there was notable improvement in clinical cardiac function indices quality of life,and exercise capacity of the patients.Conclusions This single-center retrospective study found that the use of a D-shant aSD to perform percutaneous interatrial shunting in patients with HFrEF is safe and effective.Short-term follow-up demonstrated sustained patency of the shunt and that the intervention was associated with improved functional status.
