A Case of Successful Endoscopic Submucosal Dissection of Gastric Adenoma in a Patient with Congenital Factor VII Deficiency.
10.7704/kjhugr.2015.15.1.49
- Author:
Seong Hoon KIM
1
;
Sang Hyeon CHOI
;
Jeong Wook LEE
;
Won Jae SHIN
;
Chang Seok BANG
;
Gwang Ho BAIK
Author Information
1. Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea. baikgh@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Factor VII deficiency;
Endoscopy;
Stomach neoplasms
- MeSH:
Adenoma*;
Aged;
Endoscopy;
Factor VII Deficiency*;
Factor VIIa;
Female;
Hemorrhage;
Hemorrhagic Disorders;
Humans;
Platelet Aggregation Inhibitors;
Risk Factors;
Stomach Neoplasms
- From:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
2015;15(1):49-52
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Congenital factor VII deficiency is a rare hemorrhagic disorder, and invasive procedures are likely to cause excessive bleeding in these patients. Endoscopic submucosal dissection (ESD) has been accepted as a curative treatment modality for gastric adenoma, early gastric cancer (EGC) and any other mucosal and submucosal tumors. The most important complications of ESD are bleeding and perforation. The use of antiplatelet agents or coagulopathies are risk factors for these complications. There are only few reports of successful ESD with coagulation disorders. We report a case of a 70-year-old female patient who was diagnosed with a gastric adenoma and factor VII deficiency. The patient was successfully treated with ESD. Before ESD, recombinant Coagulation factor VIIa was injected, and the procedure was performed successfully without any complications. In conclusion, ESD can be performed successfully in patients with factor VII deficiency, when recombinant human factor VIIa is administered properly.
