Short term prognosis comparison of transcatheter aortic valve replacement through the femoral artery for patients with pure aortic valve regurgitation of different annulus girths
10.3969/j.issn.1004-8812.2024.05.002
- VernacularTitle:经股动脉入路经导管主动脉瓣置换术治疗不同瓣环周长单纯主动脉瓣反流患者的短期预后比较
- Author:
Nan-Chao HONG
1
,
2
;
Sha-Sha CHEN
;
Yuan ZHANG
;
Xiao-Chun ZHANG
;
Wen-Zhi PAN
;
Da-Xin ZHOU
;
Jun-Bo GE
Author Information
1. 复旦大学附属中山医院心内科,上海 200032
2. 国家放射与治疗临床医学研究中心,上海 200032
- Keywords:
Transcatheter aortic valve replacement;
Aortic valve regurgitation;
Transfemoral;
Aortic valve annulus
- From:
Chinese Journal of Interventional Cardiology
2024;32(5):244-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate and compare the success rate and short-term clinical prognosis of transfemoral transcatheter aortic valve replacement(TF-TAVR)for patients with pure aortic regurgitation(PAR)of different annulus sizes.Methods This study is a single center retrospective study,selecting symptomatic PAR patients who received TF-TAVR treatment at Zhongshan Hospital Fudan University from September 2019 to September 2023.Based on preoperative CT results,all patients were divided into three groups:Group A(aortic annulus circumference＜80 mm),Group B(80 mm≤aortic annulus circumference＜85 mm),and Group C(aortic annulus circumference≥ 85 mm).The primary endpoint was success rate and 30d all-cause mortality,while the secondary endpoint was TAVR related complications.Results A total of 61 PAR patients were included in this study,including 27 in Group A,21 in Group B,and 13 in Group C.The overall success rate is 82.0％,and the 30 d all-cause mortality rate is 3.3％.The success rate of Group C patients was significantly lower(P=0.012),with higher rates of conversion to surgery and valve-in-valve implantation(P=0.022 and P=0.040).In terms of secondary endpoint events,there were no significant differences among the three groups in major bleeding events,major vascular complications,stroke,myocardial infarction,newly developed atrial fibrillation,implantation of new pacemakers,coronary artery occlusion,and postoperative moderate to severe perivalvular leakage(all P＞0.05).Conclusions The circumference of the aortic valve annulus is a key factor affecting the success rate of TF-TAVR in PAR,and PAR patients with an aortic valve annulus circumference less than 85mm may be more suitable for TF-TAVR.
