The relationship between the status of infarct-related artery occlusion and thrombus types in patients with non-ST-segment elevation myocardial infarction
10.3969/j.issn.1004-8812.2024.04.004
- VernacularTitle:非ST段抬高型心肌梗死患者梗死相关血管闭塞状态与血栓类型的关系
- Author:
Qing HE
1
;
Shu-Juan DONG
;
Jing-Chao LI
;
Hai-Jia YU
;
Hui-Hui SONG
;
Lu-Qian CUI
;
Ying-Jie CHU
Author Information
1. 河南省人民医院心内科,河南郑州 450003
- Keywords:
Non-ST-segment elevation myocardial infarction;
Optical coherence tomography;
Infarct-related artery;
Thrombus type
- From:
Chinese Journal of Interventional Cardiology
2024;32(4):203-210
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the status of infarct related artery(IRA)occlusion and thrombus types in patients with non-ST-segment elevation myocardial infarction(NSTEMI)using optical coherence tomography(OCT).Methods A total of 170 NSTEMI patients who underwent emergency percutaneous coronary intervention at Henan Provincial People1s Hospital from October 2021 to August 2023 and underwent OCT examination were included in the study.Among them,83 cases were in the total occlusion group and 87 cases were in the non-total occlusion group.The baseline characteristics,coronary angiography findings,and OCT results of the patients were compared and analyzed.Results Compared with the non-total occlusion group,the patients in the total occlusion group were more younger(P=0.013),the proportion of male was higher(P=0.026),and the proportion of patients with hypertension(P=0.010)and diabetes(P=0.033)was lower.In the total occlusion group,left circumflex artery(LCX)served as the main IRA,whereas in the non-total occlusion group,left anterior descending(LAD)was the predominant IRA(P=0.012);In addition,there was a significantly higher occurrence of rentrop grade Ⅱ~Ⅲ in the total occlusion group compared to the non-total occlusion group(P=0.022).The OCT results showed that in most cases,the total occlusion group was caused by plaque rupture events(P=0.014),mainly red/mixed thrombus(P<0.001);The non-total occlusion group was more commonly associated with plaque erosion events(P=0.014),with white thrombus being the main cause(P<0.001).Conclusions Total occlusion of infarct-related artery in NSTEMI patients often occurs in the LCX,and the patient is more younger,the thrombus type is mainly red/mixed thrombus,while non-total occlusion lesions are mainly white thrombus.