Risk factors for surgical site infection after transforaminal lumbar interbody fusion in treatment of lumbar degenerative diseases
- VernacularTitle:经椎间孔腰椎后路融合术治疗腰椎退变性疾病术后切口部位感染的危险因素分析
- Author:
Kang-En HAN
1
;
Hong-Wei WANG
;
Hong-Wen GU
;
Yin HU
;
Shi-Lei TANG
;
Zhi-Hao ZHANG
;
Hai-Long YU
Author Information
- Keywords: transforaminal lumbar interbody fusion; risk factors; surgical site infection
- From: Journal of Regional Anatomy and Operative Surgery 2024;33(9):810-814
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the risk factors for surgical site infection(SSI)after transforaminal lumbar interbody fusion(TLIF)for the treatment of lumbar degenerative diseases.Methods A total of 1 000 patients who underwent TLIF for lumbar degenerative diseases in our hospital were included and divided into the infection group(n=23)and the non-infection group(n=977)according to whether the surgical incision was infected.General data,surgical and laboratory indicators of patients were collected,and potential risk factors of SSI were screened by univariate analysis and multivariate regression analysis,a nomogram model was established,and its predictive efficiency was validated by the receive operating characteristic(ROC)curve.Results The incidence of SSI in patients after TLIF was 2.3%.The results of univariate analysis showed that age,operative time,intraoperative blood loss,preoperative C-reactive protein(CRP),smoking,and diabetes mellitus were the significant risk factors for the occurrence of SSI.Multivariate regression analysis showed that older age,longer operation time,more intraoperative blood loss,smoking and diabetes mellitus were the independent risk factors for postoperative SSI.ROC curve showed that the nomogram model established in this study has good predictive efficiency.Conclusion Older age,longer operation time,more intraoperative blood loss,smoking,and diabetes mellitus were independent risk factors for postoperative SSI.For patients with these high risk factors,corresponding intervention measures should be taken before operation to reduce the incidence of SSI.