Establishment of rabbit rectovaginal fistula model by magnetic compression technique
- VernacularTitle:磁压榨技术建立兔直肠阴道瘘模型
- Author:
Bo-Yan TIAN
1
;
Miao-Miao ZHANG
;
Jian-Qi MAO
;
Jia MA
;
Yi LYU
;
Xiao-Peng YAN
Author Information
- Keywords: magnetosurgery; magnetic compression technique; rectovaginal fistula; rabbit; animal model
- From: Journal of Regional Anatomy and Operative Surgery 2024;33(8):697-700
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the feasibility of establishing an animal model of rectovaginal fistula in rabbits by magnetic compression technique.Methods A magnetic device suitable for preparing rabbit rectovaginal fistula model was self-designed.Eight New Zealand female rabbits were used as experimental subjects.They were placed in a supine position after auricular intravenous anesthesia,and the magnets were placed on both sides of the rectovaginal septum through the vagina and anus,respectively,and the magnets were made to attract together.The operation time was recorded,the general state of the experimental rabbits was observed after operation,and the time of magnet discharge was recorded.The experimental rabbits were killed 1 week after operation to obtain rectovaginal fistula specimens,and the formation of rectovaginal fistula was observed by naked eye.Results The animal model of rectovaginal fistula was successfully established in 8 experimental rabbits.The operation process was smooth,with an average time of(1.63±0.70)minutes.The rabbits were generally in good condition after operation.The magnet was discharged from the body at(4.63±0.99)day after operation,and the rectovaginal fistula specimens were obtained 1 week after operation,and the rectovaginal fistula was well formed by naked eye observation.Conclusion The establishment of rabbit rectovaginal fistula model by magnetic compression technique has the advantages of simple operation and high success rate of model preparation.
