Effects of graded nutritional nursing based on Prognostic Nutritional Index in patients with cervical cancer undergoing concurrent chemoradiotherapy
10.3760/cma.j.cn115682-20220406-01647
- VernacularTitle:基于预后营养指数的分级营养护理在宫颈癌同步放化疗患者中的应用
- Author:
Yang JIN
1
;
Xiujie LI
;
Lulu XIN
;
Yang CUI
;
Yue LIU
Author Information
1. 郑州大学附属肿瘤医院（河南省肿瘤医院）妇科，郑州 453000
- Keywords:
Cervical neoplasms;
Concurrent chemoradiotherapy;
Prognostic Nutritional Index;
Graded nutritional nursing;
Nutritional support
- From:
Chinese Journal of Modern Nursing
2023;29(5):667-672
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of graded nutritional nursing based on Prognostic Nutritional Index (PNI) in patients with cervical cancer undergoing concurrent chemoradiotherapy.Methods:Totally 414 patients with cervical cancer who were treated in Henan Cancer Hospital from December 2020 to December 2021 were selected by convenience sampling, and they were randomly divided into the study group and the control group according to the random number table, with 207 patients in each group. All patients received the same concurrent chemoradiotherapy. Patients in the control group were given nutritional nursing under the guidance of NRS2002, while patients in the study group were given graded nutritional nursing based on PNI. The PNI, levels of albumin (ALB) , prealbumin (PA) , transferrin (TRF) , immunoglobulin A (IgA) , immunoglobulin G (IgG) and adverse reactions were compared between the two groups.Results:Finally, 197 patients were included in the study group, and 195 patients were included in the control group. At the eighth week of treatment, the PNI of the study group was better than that of the control group, and the difference was statistically significant ( P<0.05) . In the first and third weeks of treatment, the levels of ALB, PA, TRF, IgA and IgG in the two groups gradually decreased, but the levels of ALB, PA, TRF, IgA and IgG in the study group were higher than those in the control group, and the difference was statistically significant ( P<0.01) . During concurrent chemoradiotherapy, the incidences of nausea and vomiting, enteral nutrition intolerance, bone marrow suppression, and cancer-related fatigue in the study group were lower than those in the control group, with statistically significant differences ( P<0.05) . Conclusions:PNI-based graded nutritional nursing to cervical cancer patients undergoing concurrent chemoradiotherapy can improve the nutritional status and immune level of patients and reduce the incidence of related complications.
