An experimental study of preventive effects of Huangqi on postoperative peridural adhesion
10.3969/j.issn.1003-0034.2001.03.010
- VernacularTitle:黄芪预防术后硬膜外粘连的实验研究
- Author:
Quan SHEN
1
;
Xiao-Kui HOU
;
Cheng-Yu YE
Author Information
1. The First Affiliated Hospital of Wenzhou Medical College
- From:
China Journal of Orthopaedics and Traumatology
2001;14(3):152-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Huangqi(Chinese herb)for prevention of peridural adhesion after operation.Methods L2 and L5 laminectomy of 22 New Zealand rabbits were performed in this experimental study.Partial yellow ligament was sectioned and fat was exposed.Then the peridural fat was sectioned.The 44 vertebral lamina seyments were randomly divided into two groups of a. Huangqi group and b.Normal Saline(NS)group.The b group was control group.Huangqi liquid and NS were separately injected into the defect points of L2 and L5 vertebral lamina of the two groups.The speciments were obtained at 2nd,4th and 8th weeks after operation.Optical microscope and transmission electron microscope were used for the observation.Results There were many changes in group a:little migration of inflammation cells,small number of fibroblast and collagen,no adhesion of peridural scar,no degeneration and demyelination of spinal nerves.But in group b,adhesion of peridural scar could be seen clearly.Conclusion Huangqi has no nerve toxicity and it could be used as a good medicine to prevent postoperative peridural adhesion.
