Clinical research on rhubarb powder modulated by different excipients to intervene solid constipation in cancer patients undergoing chemotherapy
10.3760/cma.j.cn115682-20221014-05018
- VernacularTitle:不同赋形剂调制大黄粉干预肿瘤患者化疗后实性便秘的临床研究
- Author:
Kun WANG
1
;
Yanli HOU
;
Hong JU
;
Zhiqiang SONG
;
Zhizheng ZHAO
Author Information
1. 中国中医科学院广安门医院肿瘤科，北京 100053
- Keywords:
Neoplasms;
Rhubarb;
Constipation;
Excipient;
Acupoint sticking;
Kaisailu;
Sesame oil
- From:
Chinese Journal of Modern Nursing
2022;28(35):4954-4958
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of different excipients and rhubarb powder in interfering with TCM solid constipation in cancer patients undergoing chemotherapy.Methods:Totally 120 tumor patients who developed solid constipation after chemotherapy during hospitalization from May 2019 to May 2021 in the Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences by convenience sampling and divided into an observation group and a control group according to the random number table, with 60 cases in each group. On the basis of the routine treatment and nursing protocol, patients in the control group received acupoint sticking with Kaisailu and rhubarb powder, and patients in the observation group were treated with sesame oil and rhubarb powder for acupoint sticking. The effective rate of treatment, the score of Cleveland Constipation Score (CCS), and the incidence of adverse reactions were compared between the two groups.Results:After the intervention, the total effective rate in the observation group was higher than in the control group, the CCS score and the incidence of adverse reactions were lower than those of the control group, with statistically significant differences ( P<0.05) . Conclusions:Acupoint sticking of rhubarb prepared with sesame oil can better relieve chemotherapy-induced constipation than that prepared with Kaisailu, and the adverse reactions rate is low.
