Antimicrobial resistance of bacteria from intensive care units:surveillance report from Hunan Province Antimicrobial Resistance Surveillance Sys-tem,2012-2021
10.12138/j.issn.1671-9638.20245425
- VernacularTitle:湖南省细菌耐药监测网2012-2021年ICU分离细菌耐药性监测报告
- Author:
Li-Hua CHEN
1
;
Chen-Chao FU
;
Chen LI
;
Yan-Ming LI
;
Jun LIU
;
Xing-Wang NING
;
Guo-Min SHI
;
Jing-Min WU
;
Huai-De YANG
;
Hong-Xia YUAN
;
Ming ZHENG
;
Nan REN
;
Xun HUANG
;
An-Hua WU
;
Jian-Dang ZHOU
Author Information
1. 中南大学湘雅三医院检验科,湖南 长沙 410013
- Keywords:
pathogen;
antimicrobial resistance;
intensive care unit;
carbapenem-resistant Gram-negative bacteria;
Hunan Province Antimicrobial Resistance Surveillance System
- From:
Chinese Journal of Infection Control
2024;23(8):942-953
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and antimicrobial susceptibility of clinically isolated bacteria from intensive care units(ICUs)in hospitals of Hunan Province Antimicrobial Resistance Surveillance System from 2012 to 2021.Methods According to China Antimicrobial Resistance Surveillance System,data of clinically isolated bacterial strains and antimicrobial susceptibility testing results of bacteria from ICUs reported by all member units of Hunan Province Antimicrobial Resistance Surveillance System were analyzed with WHONET 2022 software.Results From 2012 to 2021,the total number of bacteria isolated from ICUs of member units of the Hunan Province Antimi-crobial Resistance Surveillance System was 5 777-22 369,with Gram-negative bacteria accounting for 76.1％-78.0％annually.Staphylococcus aureus ranked first among isolated Gram-positive bacteria each year.The top 5 bacteria among Gram-negative bacteria were Acinetobacter baumannii,Klebsiella pneumoniae,Escherichia coli,Pseudo-monas aeruginosa,and Stenotrophomonas maltophilia.Detection rate of methicillin-resistant Staphylococcus aureus showed a downward trend year by year.No Staphylococcus spp.were found to be resistant to vancomycin,teico-planin and linezolid.Detection rates of vancomycin-resistant Enterococcus faecalis and vancomycin-resistant Entero-coccus faecium were 0.6-1.1％and 0.6％-2.2％,respectively.Resistance rates of Escherichia coli and Kleb-siella pneumoniae to imipenem were 3.1％-5.7％and 7.7％-20.9％,respectively.Resistance rates of Pseudo-monasaeruginosa and Acinetobacter baumannii to imipenem were 24.6％-40.1％and 76.1％-80.9％,respective-ly.Detection rates of carbapenem-resistant Pseudomonas aeruginosa declined year by year.Acinetobacter baumannii maintained high susceptibility to polymyxin B,with resistance rate＜10％.Conclusion Antimicrobial resistance of bacteria from ICUs is serious.Carbapenem-resistant Enterobacteriales has an upward trend after 2019.It is nece-ssary to strengthen the surveillance of bacterial resistance and carry out multidisciplinary collaboration.
