Environmental hygiene and healthcare-associated infection:a time-series study based on generalized additive model
10.12138/j.issn.1671-9638.20245324
- VernacularTitle:环境卫生与医院感染的时间序列研究:基于广义相加模型(GAM)
- Author:
Kai LIN
1
,
2
;
Kun CHEN
;
Jian-Bing WANG
;
Fang-Hua FAN
;
Hui LIANG
;
Fang CHEN
;
Kai-Ling JIN
;
Wen-Jie CHU
;
Wei-Guo CHEN
;
Huan SHAN
Author Information
1. 浙江大学公共卫生学院,浙江杭州 310058
2. 浙江医院医院感染管理科,浙江杭州 310058
- Keywords:
healthcare-associated infection;
time-series analysis;
generalized additive model;
environmental hy-giene;
hand hygiene
- From:
Chinese Journal of Infection Control
2024;23(7):798-805
- CountryChina
- Language:Chinese
-
Abstract:
Objective To quantitatively analyze the impact of environmental hygiene on the occurrence of health-care-associated infections(HAI).Methods Monitoring data of HAI and environmental hygiene from a tertiary first-class hospital from January 2018 to December 2022 were collected,and the impact of environmental bacterial colony forming unit(CFU)on the occurrence of HAI was analyzed by a time-series generalized additive model.Results The single-contamination model showed a significant positive correlation between HAI and staff's hand bacterial CFU(β1=0.009,P=0.012).For an increase of 1 interquartile range(IQR)in the monthly mean CFU per dish(MCFU/Dish)of staffs'hand,the incidence of HAI increased by 13.28％(95％CI:2.82％-24.81％).Subgroup and lag effect analysis showed that when the monthly MCFU/Dish(after hand disinfection)of staffs'hand in-creased by one IQR,the excess risk(ER)of HAI for the month(lag0)was 16.26％(95％CI:15.45％-17.09％).In the multi-contamination model,the correlation between surface contamination and HAI was also statistically sig-nificant.Conclusion There is a significant correlation between hospital environmental hygiene and the occurrence of HAI.
