Evaluation on the effect of applying comprehensive interventions on pro-moting pathogen detection before antimicrobial therapy in hospitalized pa-tients
10.12138/j.issn.1671-9638.20243832
- VernacularTitle:应用综合干预措施对促进住院患者抗菌药物治疗前病原学送检的效果评价
- Author:
ZHUYi
1
;
Jian-Wen ZHUANG
;
Ying-Ying PAN
;
Li-Na ZOU
;
Yu-Rong HUANG
Author Information
1. 新疆生产建设兵团医院 石河子大学医学院第二附属医院医院感染管理与控制办公室,新疆乌鲁木齐 830002
- Keywords:
pathogen detection;
comprehensive intervention;
detection rate;
antimicrobial agent;
evaluation of effect
- From:
Chinese Journal of Infection Control
2024;23(5):600-604
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of applying comprehensive interventions on promoting pathogen detec-tion before antimicrobial therapy in hospitalized patients.Methods Hospitalized patients who received therapeutic use of antimicrobial agents in a tertiary first-class hospital from January 2020 to December 2021 were selected as the research subjects.Comprehensive intervention measures were implemented from January 2021.The pathogen detec-tion rates,detection classification,and detection rates of key monitored departments before antimicrobial therapy were compared between the pre-intervention group(January-December 2020)and the post-intervention group(Janu-ary-December 2021).Results A total of 10 239 hospitalized patients who received therapeutic use of antimicrobial agents were included in analysis,4 526 cases were in the pre-intervention group and 5 713 cases in the post-interven-tion group.The pathogen detection rates before antimicrobial therapy,before restricted grade antimicrobial therapy,and before special grade antimicrobial therapy after intervention were 94.56％,94.72％,and 96.03％,respective-ly,which were higher than 83.74％,84.47％,and 84.95％before intervention,with statistical significance(all P＜0.05).The detection rate of targeted pathogens after intervention was 64.87％,higher than that before interven-tion(28.04％),with statistically significant difference(P＜0.05).The pathogen detection rates before therapeutic use of antimicrobial agents in departments of critical care medicine,pulmonary and critical care medicine,pediatrics,neurosurgery,and general surgery after intervention were 93.20％,91.17％,92.20％,94.12％,and 91.15％,re-spectively,higher than the rates before intervention,namely 85.00％,82.19％,83.20％,83.33％,and 83.03％,respectively,with statistical significance(all P＜0.05).Conclusion The application of comprehensive intervention measures can improve the pathogen detection rate before antimicrobial therapy of hospitalized patients.Close atten-tion should be paid to the pathogen detection indicators related to healthcare-associated infection diagnosis and for the detection of sterile body fluid.
